Intracranial pressure affects retinal venular complexity in idiopathic intracranial hypertension: a retrospective observational study

Autor:	Le Cao, Hang Wang, William Robert Kwapong, Zhouwei Xiong, Yitian Zhao, Guina Liu, Rui Liu, Junfeng Liu, Fayun Hu, Bo Wu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Idiopathic intracranial hypertension Retinal venules Retinal arterioles Intracranial pressure Papilledema Neurology. Diseases of the nervous system RC346-429
Zdroj:	BMC Neurology, Vol 24, Iss 1, Pp 1-9 (2024)
Druh dokumentu:	article
ISSN:	1471-2377
DOI:	10.1186/s12883-024-03881-z
Popis:	Abstract Background Increased intracranial pressure (ICP) in patients with idiopathic intracranial hypertension (IIH) affects the retinal microvasculature, which can be imaged and quantified by optical coherence tomography angiography (OCTA). We aimed to identify the mediating factor between ICP and OCTA parameters association in IIH patients. Methods IIH patients with active intracranial hypertension were enrolled. OCTA imaging was performed after ICP measurement. We quantified the branching complexity of the retinal arterioles and venules from the superficial vascular complex of the OCTA image. Eyes of IIH patients were stratified into eyes with papilledema (IIH-P) and eyes without papilledema (IIH-WP). All participants underwent visual acuity (VA) examination. Results One hundred and thirty-eight eyes from 70 IIH patients and 146 eyes from 73 controls were included. Compared to the control group, IIH patients and IIH-P had reduced arteriole complexity and increased venule complexity (p
Databáze:	Directory of Open Access Journals
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