Visible light-promoted synthesis of 2-aryl-(3-organoselanyl)thieno[2,3-b]pyridines
| Autor: | Ricardo Hellwig Bartz, Thiago Jacobsen Peglow, Filipe Penteado, Raquel Guimarães Jacob, Eder João Lenardão, Gelson Perin |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Green Chemistry Letters and Reviews, Vol 15, Iss 2, Pp 373-382 (2022) |
| Druh dokumentu: | article |
| ISSN: | 17518253 1751-7192 1751-8253 |
| DOI: | 10.1080/17518253.2022.2065891 |
| Popis: | We describe a simple and environment-friendly visible light-promoted protocol to access 2-aryl-(3-organoselanyl)thieno[2,3-b]pyridines, through the selenocyclization of 3-(arylethynyl)-2-(alkylthio)pyridines in the presence of diorganyl diselenides as selenium source. The Se-based reactive species were generated in situ by the homolytic Se-Se bond cleavage using blue LED in an O2 atmosphere at room temperature. The protocol was suitable for a wide range of substrates bearing different substituents, allowing the synthesis of twenty-one thieno[2,3-b]pyridines in good to excellent yields (57–99%). |
| Databáze: | Directory of Open Access Journals |
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