| Autor: |
Ashwin Ravichandran, MD, Naga Venkata K. Pothineni, MD, Jaimin R. Trivedi, MD, MPH, Henri Roukoz, MD, Mustafa M. Ahmed, MD, Adarsh Bhan, MD, Geetha Bhat, MD, Jennifer Cowger, MD, Amin Al Ahmad, MD, FHRS, Andrea Natale, MD, FHRS, Luigi Di Biase, MD, FHRS, Mark S. Slaughter, MD, Dhanunjaya Lakkireddy, MD, FHRS, Rakesh Gopinathannair, MD, MA, FHRS |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Heart Rhythm O2, Vol 2, Iss 6, Pp 691-697 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2666-5018 |
| DOI: |
10.1016/j.hroo.2021.09.005 |
| Popis: |
Background: Limited data exist regarding complication rates of implantable cardioverter-defibrillators (ICD) and cardiac resynchronization therapy devices (CRT-D) in patients with left ventricular assist devices (LVAD). Objective: We describe the incidence and characteristics of ICD- and CRT-D-related procedures and complications in a multicenter LVAD cohort. Methods: A total of 537 LVAD patients with a pre-existing ICD or CRT-D from 5 centers were included. Details on device type, device therapies, procedural complications, and long-term survival were analyzed. Results: Of 537 patients, 280 had a CRT-D and 257 had ICD only. During a median follow-up of 538 days, 126 patients underwent generator replacement with significantly higher rate in the CRT group (79 [28.2%] vs 47 [18.3%], P = .0006). Device-related complications occurred in 36 (13%) CRT-D and 20 (8%) ICD patients (P = .06). Incidence of pocket hematoma (3.2% vs 2.7%), infection (4.3% vs 1.6%), and lead malfunction (3.1% vs 2.8%) was similar in both groups, with no effect of device complication on long-term survival (log-rank P = .7). There was a higher incidence of post-LVAD antitachycardia pacing for ventricular arrhythmias in the CRT-D group compared to the ICD group (35% vs 26%, P = .03). Conclusion: Cardiac implantable electronic device–related procedures are common in LVAD patients. Compared to ICD only, continued CRT-D therapy post-LVAD results in a significantly higher number of generator changes and a trend towards higher device- or lead-related complications. Device-related complications were not associated with reduced survival. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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