Does the use of polymethyl-methacrylate cement after intralesional curettage of giant cell tumors of appendicular bone guarantee reduced local recurrence rates? A retrospective analysis

Autor: Thomas Colding-Rasmussen, Peter F Horstmann, Peter H Jørgensen, Werner Hettwer, Bjarne H Hansen, Christian Nai En Tierp-Wong, Michael M Petersen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Orthopaedic Surgery, Vol 31 (2023)
Druh dokumentu: article
ISSN: 2309-4990
10225536
DOI: 10.1177/10225536231202155
Popis: Purpose Polymethyl-methacrylate cement (PMMA) is often used as bone defect reconstruction material after surgical removal of giant cell tumors. The purpose of this study was to investigate if the application of PMMA improves the local recurrence rates for giant cell tumors (GCT) of appendicular bone treated with intralesional curettage. Methods A retrospective analysis of all appendicular GTCs treated at two major Danish sarcoma centres between the 1 st of January 1998 and December 31 st 2013; minimum follow-up of 3.0 years (median: 8.9; 1.3–18.7 years). Kaplan-Meier survival model, log-rank and multivariate Cox regression were used to calculate and compare local recurrence rates. p -values
Databáze: Directory of Open Access Journals