Trends, outcomes, and factors associated with in-hospital opioid overdose following major surgery

Autor: Joanna Curry, Troy Coaston, Amulya Vadlakonda, Sara Sakowitz, Saad Mallick, Nikhil Chervu, Baran Khoraminejad, Peyman Benharash
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Surgery Open Science, Vol 18, Iss , Pp 111-116 (2024)
Druh dokumentu: article
ISSN: 2589-8450
DOI: 10.1016/j.sopen.2024.03.002
Popis: Background: With the growing opioid epidemic across the US, in-hospital utilization of opioids has garnered increasing attention. Using a national cohort, this study sought to characterize trends, outcomes, and factors associated with in-hospital opioid overdose (OD) following major elective operations. Methods: We identified all adult (≥18 years) hospitalizations entailing select elective procedures in the 2016–2020 National Inpatient Sample. Patients who experienced in-hospital opioid overdose were characterized as OD (others: Non-OD). The primary outcome of interest was in-hospital OD. Multivariable logistic and linear regression models were developed to evaluate the association between in-hospital OD and mortality, length of stay (LOS), hospitalization costs, and non-home discharge. Results: Of an estimated 11,096,064 hospitalizations meeting study criteria, 5375 (0.05 %) experienced a perioperative OD. Compared to others, OD were older (66 [57–73] vs 64 [54–72] years, p
Databáze: Directory of Open Access Journals