Autor: |
Sandra Trindade, Mariana De Niz, Mariana Costa-Sequeira, Tiago Bizarra-Rebelo, Fábio Bento, Mario Dejung, Marta Valido Narciso, Lara López-Escobar, João Ferreira, Falk Butter, Frédéric Bringaud, Erida Gjini, Luisa M. Figueiredo |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-022-34622-w |
Popis: |
Trypanosoma brucei parasites invade different organs, such as the central nervous system, adipose tissue, and skin in mammalian host. Here, Trindade et al. perform mathematical modelling to show that adipose tissue forms (ATFs) grow slower than the bloodstream forms and experimentally characterize the heterogeneous ATF populations and provide evidence that slow-growing forms are refractory to drug treatment. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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