| Autor: |
S. Fidler, S. Lewin, S. Deeks, O.S. Sogaard, L. Vandekerckhove, S. Collins, D. Kelly, J. Singh, M. Caskey, J. Frater |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Journal of Virus Eradication, Vol 7, Iss 1, Pp 100025- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2055-6640 |
| DOI: |
10.1016/j.jve.2020.100025 |
| Popis: |
This discussion paper addresses the safety of HIV cure studies, particularly those involving stopping antiretroviral therapy, known as an analytic treatment interruption (ATI) in the context of the SARS-CoV-2 pandemic. More than 30 studies listed on ClinicalTrials.gov include an ATI and many others were planned to begin over the next 12 months but most were halted due to the COVID-19 pandemic. We consider the ethics, risks and practical considerations to be taken into account before re-opening HIV cure clinical trials, noting the specific risks of ATI in the context of circulating SARS-CoV-2. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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