Autor: |
Ana Laura Martins de Andrade, Julia Risso Parisi, Patrícia Brassolatti, Nivaldo Antonio Parizotto |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
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Zdroj: |
Acta Cirúrgica Brasileira, Vol 32, Iss 10, Pp 836-842 (2017) |
Druh dokumentu: |
article |
ISSN: |
0102-8650 |
DOI: |
10.1590/s0102-865020170100000005 |
Popis: |
Abstract Purpose: To present an alternative experimental model of third degree burn of easy reproducibility. Methods: Eighteen male Wister rats were randomly divided into three groups, 6 of which were allocated to each group. A soldering iron coupled to an aluminum plate was used to produce burn, at a temperature of 150ºC, with different exposure times per group. Group 5 (G5) animals were burned at 150°C with exposure time of 5 seconds; Group 10 (G10) the animals were burned at 150°C with exposure time of 10 seconds and group 15 (G15) the animals were burned at 150°C with exposure time of 15 seconds. Results: Histopathological analyzes showed that all three groups had similar morphological characteristics, with total thickness involvement. Conclusion: The technique is effective to reproduce a third degree burn and suggests the temperature of 150ºC with 5 seconds of exposure in order to minimize the risks to the animals. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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