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Yujing Zhang,1,* Haiqian Wang,2,* Lei Bai,1 Xiaodong Li,1 Li Liu,1 Liang Wang3 1Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 2Department of Outpatient, General Hospital of Ningxia Medical University, Yinchuan, 750004, People’s Republic of China; 3Department of Interventional Therapy and Vascular Surgery, Dongguan People’s Hospital, Dongguan, 523059, People’s Republic of China*These authors contributed equally to this workCorrespondence: Liang Wang, Department of Interventional Therapy and Vascular Surgery, Dongguan People’s Hospital, Dongguan, 523059, People’s Republic of China, Email nx.vascular@hotmail.comObjective: To establish the endovascular repair and prognosis of patients with aorto-iliac aneurysm and Brucella abortus infection.Methods: From September 2018 to September 2021, seven cases of Brucella abortus infection with aorto-iliac aneurysm were treated by the endovascular aneurysm repair (EVAR) procedure. Clinical and imaging data were collected to evaluate the therapeutic results, including body temperature, blood culture, imaging manifestations, stent patency and endoleak during the postoperative and follow-up periods.Results: Except for one patient who died of acute hematemesis and hematochezia just after the admission, seven patients were treated successfully. The aneurysms were completely excluded, and all stent grafts were patent. Patients were followed up for 12– 32 months, with an average follow-up of 18.5 ± 9.1 months. There were no cases of endoleak, infection recurrence, gluteal muscle ischemia or spinal cord ischemia during the follow-up period.Conclusion: It is feasible to treat Brucella abortus-infected aneurysms with the EVAR procedure. The results were optimistic in the short and medium-term. The application of sensitive antibiotics before and after the operation is the cornerstone of endovascular therapy. However, the long-term results require further follow-up.Keywords: Brucella abortus infection, aorto-iliac aneurysm, endovascular aneurysm repair, bacterial infection, zoonosis, mycotic aneurysm |