| Autor: |
Jie Yang, Yisong Cheng, Ruoran Wang, Bo Wang |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
BMC Geriatrics, Vol 22, Iss 1, Pp 1-10 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2318 |
| DOI: |
10.1186/s12877-022-02920-z |
| Popis: |
Abstract Background Phosphate disturbances are relatively common in hospitalized patients, especially in critically ill patients. The abnormal phosphate levels may indicate an abnormal body condition. However, little is known about the association between elevated serum phosphate and outcome in critically ill elderly patients. Therefore, the purpose of the present study was to investigate the association between early elevated phosphate and mortality in critically ill elderly patients. Methods The present study was a retrospective cohort study based on the medical information mart for intensive care IV (MIMIC-IV) database. Patients with age ≥60 years old were enrolled in the present study. The primary outcome in the present study was ICU mortality. Univariate and multivariate Cox proportional hazard regression analyses were used to evaluate the association between early elevated phosphate and ICU mortality in critically ill elderly patients. Results Twenty-four thousand two hundred eighty-nine patients were involved in this analysis and 2,417 patients died in ICU. The median age of involved patients was 78.4 (67.5, 82.9) years old. The median level of serum phosphate in the survivor group was 3.6 (3.0, 4.3) mg/dL, and the median level of serum phosphate in the non-survivor group was 4.4 (3.4, 5.8) mg/dL. The level of serum phosphate in the non-survivor group was significantly higher than the survivor group (4.4 vs. 3.6, P |
| Databáze: |
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| Externí odkaz: |
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