MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery

Autor: David J. Wooten, Christian T. Meyer, Alexander L. R. Lubbock, Vito Quaranta, Carlos F. Lopez
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-24789-z
Popis: The lack of a unifying metric characterizing combinatorial drug interactions has impeded the development of combinatorial therapies. Here, the authors present MuSyC, a consensus synergy metric that overcomes several caveats associated with other, popular metrics.
Databáze: Directory of Open Access Journals