Association between Hemoglobin A1c and Stroke Risk in Patients with Type 2 Diabetes
| Autor: | Yun Shen, Lizheng Shi, Elizabeth Nauman, Peter Katzmarzyk, Eboni Price-Haywood, Alessandra Bazzano, Somesh Nigam, Gang Hu |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Journal of Stroke, Vol 22, Iss 1, Pp 87-98 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2287-6391 2287-6405 |
| DOI: | 10.5853/jos.2019.01704 |
| Popis: | Background and Purpose The association between hemoglobin A1c (HbA1c) and stroke risk along with its subtypes is rarely reported. We aimed to investigate the association between HbA1c and the risk of incident stroke in patients with type 2 diabetes based on real world data from three healthcare systems. Methods We performed a retrospective cohort study of 27,113 African Americans and 40,431 whites with type 2 diabetes. Demographic, anthropometric, laboratory, and medication information were abstracted from the National Patient-Centered Clinical Research Network common data model. Incident stroke events including both ischemic and hemorrhagic stroke were defined. Results During a mean follow-up period of 3.79±1.68 years, 7,735 patients developed stroke (6,862 ischemic and 873 hemorrhagic). Multivariable-adjusted hazard ratios across levels of HbA1c at baseline ( |
| Databáze: | Directory of Open Access Journals |
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