Rheumatoid Arthritis Flare-ups Following Immunization with Sinopharm Inactivated Virus-based COVID-19 Vaccine

Autor: Parisa Delkash, Amir Azimi, Niloufar Taherpour, Alireza Rajaei, Faraneh Farsad, Saeid Haji Aghajani
Jazyk: English<br />Persian
Rok vydání: 2023
Předmět:
Zdroj: طب اورژانس ایران, Vol 10, Iss 1 (2023)
Druh dokumentu: article
ISSN: 2383-3645
DOI: 10.22037/ijem.v10i1.42970
Popis: Introduction: This study aimed to investigate the incidence of rheumatoid arthritis (RA) flare-ups following immunization with the Sinopharm COVID-19 inactivated virus-based vaccine. Methods: We conducted a retrospective observational study at the Rheumatology Clinic of Imam Hossein Hospital, incorporating 200 RA patients in remission undergoing non-biologic Disease-Modifying Antirheumatic Drugs (DMARDs) treatments. A rheumatologist confirmed a flare-up based on patients complain of arthralgia and joint stiffness and complete examination of joints over a three-month period following vaccination. Results: Twelve percent of all included patients experienced symptom recurrence. The average age of patients with flare-ups was significantly higher, but no gender-based differences were observed (p
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