A Comparison of Accuracy between IMMULITE2000® and GENEDIA® for Helicobacter pylori Infection

Autor: Seon Hee Lim, Nayoung Kim, Sung Eun Kim, Gwang Ho Baik, Ju Yup Lee, Kyung Sik Park, Jeong Eun Shin, Hyun Joo Song, Dae-Seong Myung, Suck Chei Choi, Hyun Jin Kim
Jazyk: English<br />Korean
Rok vydání: 2020
Předmět:
Zdroj: The Korean Journal of Helicobacter and Upper Gastrointestinal Research, Vol 20, Iss 1, Pp 54-62 (2020)
Druh dokumentu: article
ISSN: 1738-3331
DOI: 10.7704/kjhugr.2019.0014
Popis: Background/Aims In serological tests for Helicobacter pylori (H. pylori), an enzyme-linked immunosorbent assay (GENEDIA®) and a solid-phase, two-step chemiluminescent enzyme immunoassay (IMMULITE®), which are easy to perform, inexpensive, and widely available, are commonly used. However, local validation of the test performance of IMMULITE® is required. This study aimed to examine the performance of IMMULITE® in comparison with that of GENEDIA® in a Korean health checkup population. Materials and Methods The sera of 300 subjects among those who underwent health checkup were analyzed using IMMULITE®, and results were compared with those of GENEDIA®. The two serological tests were compared for their ability to predict atrophic gastritis (AG) or intestinal metaplasia (IM) on endoscopy. Results We found significant correlation (Pearson correlation coefficient=0.903, P
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