Topical treatment of inherited epidermolysis bullosa
| Autor: | Alexey A. Kubanov, Vadim V. Chikin, Arfenya E. Karamova, Ekaterina S. Monchakovskaya |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Vestnik Dermatologii i Venerologii, Vol 97, Iss 6, Pp 6-19 (2021) |
| Druh dokumentu: | article |
| ISSN: | 0042-4609 2313-6294 |
| DOI: | 10.25208/vdv1290 |
| Popis: | Inherited epidermolysis bullosa is a group of genetic skin disorders characterized by skin erosions, ulceration, skin and mucosal blistering requiring topical treatment. This review demonstrates major clinical manifestations of epidermolysis bullosa and its mechanisms of development. According to these features the main principles of topical treatment and drug therapy were developed, including physical protection from trauma, moisturizing, improvement of wound healing, prevention and management of infection, itch and pain management. Drug therapy is outlined with dosage forms, drug routes of administration, age restrictions indicated in the instruction for medical use for the medications that could be used in epidermolysis bullosa patients. The authors provide indications for clinical use of antiseptics, disinfectants, antibiotics, antimicrobial agents, emollient cream and drugs reducing itch and pain. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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