Posaconazole aggravates vincristine-related hypertension in children with acute lymphoblastic leukemia: a case report
| Autor: | Chao Lin, Guohua Chen, Junbin Huang, Yucai Cheng, Yahong Xu, Airun Zhang, Hongman Xue, Chun Chen |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Journal of International Medical Research, Vol 48 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1473-2300 03000605 |
| DOI: | 10.1177/0300060520969579 |
| Popis: | Vincristine-related secondary hypertension is rare. This study reports two children who were treated with vincristine for acute lymphoblastic leukemia (ALL) and posaconazole for fungal infections who experienced vincristine-related secondary hypertension. Blood pressure normalized in both children after halting the drugs and providing antihypertensive treatment. Thus, posaconazole can interact with vincristine and induce secondary hypertension in children with ALL. As an adverse event, this interaction is a rare occurrence. |
| Databáze: | Directory of Open Access Journals |
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