Application of the postnatal urinary tract dilation classification system to predict the need for surgical intervention among neonates and young infants

Autor: Jisun Hwang, Pyeong Hwa Kim, Hee Mang Yoon, Sang Hoon Song, Ah Young Jung, Jin Seong Lee, Young Ah Cho
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Ultrasonography, Vol 42, Iss 1, Pp 136-146 (2023)
Druh dokumentu: article
ISSN: 2288-5919
2288-5943
DOI: 10.14366/usg.22035
Popis: Purpose The aim of this study was to validate the postnatal urinary tract dilation (UTD) classification system by correlating it with the need for surgical intervention. Methods Young infants who underwent ultrasound (US) examinations for prenatal hydronephrosis were retrospectively identified. The kidney units (KUs; right, left, or bilateral) were graded from UTD P0 (very low risk) to P3 (high risk) based on seven US criteria from the UTD system. Surgery-free survival curves were constructed using the Kaplan-Meier method. Univariable and multivariable Cox proportional-hazards regression analysis clustered by patients was performed. Interobserver agreement was analyzed using the weighted kappa coefficient. Results In total, 504 KUs from 336 patients (mean age, 18.3±15.9 days; range, 1 to 94 days; males, n=276) were included, with a median follow-up of 24.2 months. Fifty-eight KUs underwent surgical intervention. Significant differences were observed among the Kaplan-Meier curves stratified into UTD groups (P
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