The Effects Of Surgical Arthroscopy And Intraarticular Medication On The Antioxidant System And Lipid Peroxidation In Knee Osteoarthritis
| Autor: | Idris Perktaş, Metin Lütfi Baydar |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Ķazaķstannyṇ Klinikalyķ Medicinasy, Vol 21, Iss 3, Pp 32-36 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1812-2892 2313-1519 |
| DOI: | 10.23950/jcmk/14643 |
| Popis: | Aim: This study aims to evaluate the effects of joint surgery through arthroscopy, intraarticular medication, and antioxidant therapy on the antioxidant system and lipid peroxidation in patients with knee osteoarthritis (KOA). The study examines the ability of high-molecular weight hyaluronan, sodium hyaluronate, and oral Vitamin E to modulate oxidative stress markers in the knee joint. Methods and Materials: There were 60 patients diagnosed with KOA that were divided into four groups according to the type of treatment for this prospective study at the Department of Orthopaedics and Traumatology. Blood and synovial fluid samples collected before and after treatment were evaluated for superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), lipid peroxidation (malondialdehyde, MDA) catalase (CAT). SPSS software was used to perform statistical analysis where the significance level was set at p |
| Databáze: | Directory of Open Access Journals |
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