Febrile seizures: is there a significance of chronological ranking of fever and seizure?

Autor: Turgay Cokyaman
Jazyk: English<br />Turkish
Rok vydání: 2019
Předmět:
Zdroj: Family Practice and Palliative Care, Vol 4, Iss 2, Pp 57-61 (2019)
Druh dokumentu: article
ISSN: 2459-1505
DOI: 10.22391/fppc.491220
Popis: Introduction:Seizures observed in febrile disease periods in healthychildren aged from 3 months to 6 years are known as febrile seizures (FS).There is usually a chronological sequence involving seizure following fever inmost FS, but some cases may not follow this pattern. This study investigatedthe chronological relation between fever and convulsion and whether clinicaland laboratory findings affect this. Methods:Patients with FS between 1 December, 2015, and 1 April,2016, were included in this study. Cases with a regular fever plus seizurechronological sequence were classified as classical FS. Without a regularchronological sequence, fever after seizure, were classified as non-classicalFS. The effect on both groups of parameters such as gender, age, height,weight, type of FS (simple or complex), previous history of FS, family history of FS, family history of epilepsy, qualitative c-reactive protein(CRP) and white blood cell (WBC) count were evaluated. Results:Twenty-seven percent of FS were non-classical and 73% wereclassical. Negative CRP and low WBC emerged as significant predictors ofnon-classical FS at binary logistic regression (OR=1.388, 95% CI 1.051-1.834and OR=9.021, 95% CI 1.298-62.702, respectively). Other factors such as gender,age, height, weight, type of FS, previous history of FS, familyhistory of FS, familyhistory of epilepsyhad no effect in terms of nonclassicFS. Conclusions:Acute inflammatory response findings such as increased CRP,WBC and fever may not accompany in non-classical FS. Although the diagnosis ofFS is correct in such cases, misunderstandings may occur between the physicianand parents because of the nomenclature employed.
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