EFFECT OF GELATIN AS A BINDER ON TURMERIC EXTRACT TABLET FORMULATION
| Autor: | Adi Permadi, Iis Wahyuningsih, Sapto Yuliani, Ibdal Satar, Ratna Wijayatri |
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| Jazyk: | indonéština |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Jurnal Farmasi Sains dan Praktis, Vol 8, Iss 2 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2549-9068 2579-4558 |
| DOI: | 10.31603/pharmacy.v8i2.6399 |
| Popis: | The main components for tablet formulations are the fillers, binders, crushers, thinners and lubricants. Among these components, the binders play a key role on the powder cohesion properties during the formation of tablet granules. In this study, turmeric extract tablets were formulated using 15 g of turmeric extract, 35 g of aerosil, 12.8 g of lactose, 1% magnesium stearate, 200 ml of aquadest and gelatin as a binder. To evaluate the effect of gelatin on the tablet formulation, the gelatin was then prepared in different formulation namely 0.1 g (formulation A), 0.2 g (formulation B) and 0.5 g (formulation C), respectivley. Based on the tablet properties, the turmeric tablet with formulation C met the standard requirements of friability less than 1%, the hardness in the range of 4 -8 kg and disintegration time under 15 minutes. |
| Databáze: | Directory of Open Access Journals |
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