Parent and patient knowledge and attitudes about cancer predisposition syndrome genetic testing in pediatric oncology: Understanding sociodemographic and parent–child differences

Autor: Chelsea S. Rapoport, Diane Masser‐Frye, Sapna Mehta, Alyssa K. Choi, Sydney Olfus, Megan Korhummel, Veronica Hoyo, David Dimmock, Vanessa L. Malcarne, Dennis J. Kuo
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Cancer Reports, Vol 7, Iss 9, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2573-8348
DOI: 10.1002/cnr2.2119
Popis: Abstract Background Cancer predisposition syndromes (CPS) impact about 10% of patients with pediatric cancer. Genetic testing (CPS‐GT) has multiple benefits, but few studies have described parent and child knowledge and attitudes regarding CPS‐GT decision‐making. This study examined parent and patient CPS‐GT decision‐making knowledge and attitudes. Procedure English‐ or Spanish‐speaking parents of children with pediatric cancer and patients with pediatric cancer ages 15–18 within 12 months of diagnosis or relapse were eligible to participate. Seventy‐five parents and 19 parent‐patient dyads (N = 94 parents, 77.7% female, 43.6% Latino/a/Hispanic; 19 patients, 31.6% female) completed surveys measuring CPS‐GT‐related beliefs. Independent samples t‐tests compared parent responses across sociodemographic characteristics and parent‐patient responses within dyads. Results Spanish‐speaking parents were significantly more likely than English‐speaking parents to believe that CPS‐GT not being helpful (p
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