Factors Influencing Disability and Quality of Life during Treatment: A Cross-Sectional Study on IBD Patients

Autor: Carla Marinelli, Edoardo Savarino, Marco Inferrera, Greta Lorenzon, Alessandra Rigo, Matteo Ghisa, Sonia Facchin, Renata D’Incà, Fabiana Zingone
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Gastroenterology Research and Practice, Vol 2019 (2019)
Druh dokumentu: article
ISSN: 1687-6121
1687-630X
DOI: 10.1155/2019/5354320
Popis: Background/Aim. Inflammatory bowel disease (IBD) is a chronic disorder affecting patients’ quality of life and increasing their disability. The aim of our study was to evaluate clinical and pharmacological factors associated with impaired quality of life and disability in a large cohort of IBD patients during IBD treatment. Methods. We consecutively and prospectively recruited all IBD patients referred to the IBD Unit of the “Azienda Ospedaliera” of Padua. Demographics and clinical information were collected, and all patients completed the IBD questionnaire (IBDQ) and the IBD-Disability Index (IBD-DI) questionnaire. A multivariate regression model and Spearman’s rank correlation coefficient were applied for detecting IBD-related variables relevant to disability and quality of life. Results. We included 435 IBD patients. Multivariate regression modelling identified active disease, anaemia, presence of extraintestinal manifestations, and Crohn subtype as independent predictors for both disability and poor quality of life. We observed a strong positive correlation between IBD-DI and IBDQ (r=0.84, p
Databáze: Directory of Open Access Journals
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