| Autor: |
Mina Alimohammadi, Yasaman Gholinezhad, Vahide Mousavi, Samaneh Kahkesh, Malihe Rezaee, Alireza Yaghoobi, Alireza Mafi, Mahmood Araghi |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 645-669 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1611-2156 |
| DOI: |
10.17179/excli2023-6209 |
| Popis: |
Circular RNAs (CircRNAs) are a class of regulatory RNA transcripts, which are ubiquitously expressed in eukaryotes. CircRNA dysregulation has been shown to disrupt the interaction of the Wnt/β-catenin pathway, which regulates several biological processes involved in tumorigenesis, thereby contributing to the development and progression of cancer. Interactions of tumor-derived circRNAs with the Wnt/β-catenin signaling pathway provide both clinical diagnostic biomarkers and promising therapeutic targets. In this review, we outlined current evidence on the roles of circRNAs associated with the Wnt/β-catenin pathway in regulating lung cancer formation and development. We believe that our findings will assist in the advancement or establishment of circRNA-based lung cancer therapeutic approaches. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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