Effect on clinical and neonatal outcomes of blastocelic microsuction prior to vitrification

Autor:	Shingo Mitsuhata, Yuji Endo, Momoko Hayashi, Yoshitaka Fujii, Hiroaki Motoyama
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	artificial shrinkage blastocyst clinical and neonatal outcomes microsuction vitrification Diseases of the endocrine glands. Clinical endocrinology RC648-665 Reproduction QH471-489
Zdroj:	Reproductive Medicine and Biology, Vol 18, Iss 3, Pp 284-289 (2019)
Druh dokumentu:	article
ISSN:	1447-0578 1445-5781
DOI:	10.1002/rmb2.12273
Popis:	Abstract Purpose Microsuction (MS) is a technique for mechanically emptying fluid from blastocele using a microneedle. In this study, we evaluated the improvement in clinical and neonatal outcomes of vitrified blastocyst transfer programs when MS of blastocelic fluid was used before vitrification. Methods This was a retrospective study based on data collected between March 2014 and August 2016. A total of 317 blastocysts obtained from 211 patients were analyzed. The blastocelic fluid of expanded blastocysts was aspirated completely, and blastocysts were collapsed prior to vitrification. Clinical and neonatal outcomes of warmed blastocysts were compared. Results The survival rate of the MS blastocyst was significantly higher compared with the nontreatment control (98.7% vs 89.3%, OR: 9.34, 95% CI: 2.35‐36.8, P
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