Consumption of antibacterials in three hospitals in Santiago de Cuba in the period 2019-2020

Autor: Maraelys Morales-González, Clara A. Zúñiga-Moro, Oneyda Clapé-Laffita, Elianis García-Díaz, Tania Quintana-Hernández, Niurka M. Dupotey-Varela, Maryenis Rodríguez-Alfaro, Lourdes Serpa-Hernández
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2022
Předmět:
Zdroj: Journal of Pharmacy & Pharmacognosy Research, Vol 10, Iss 6, Pp 986-994 (2022)
Druh dokumentu: article
ISSN: 0719-4250
DOI: 10.56499/jppres22.1453_10.6.986
Popis: Context: Infections by multiresistant bacteria increase the risk of therapeutic failure, increasing hospital stay, costs and mortality. This determines the use of more expensive antibacterials with a broader spectrum, which leads to a high consumption at the hospital level, which increases bacterial resistance. Aims: To characterize the consumption of antibacterials in three hospitals in Santiago de Cuba. Methods: A descriptive and cross-sectional study of consumption was carried out. The consumed units, anatomical, therapeutic, and chemical classification, route of administration and price were analyzed for each antimicrobial. The defined daily dose (DDD)/100 beds/day and the cost of antibacterials for systemic use were determined. Descriptive statistics were used. Results: The most used antibacterial in both years (2019 and 2020) was ceftriaxone (12.6% and 26.9%). The most used group was J01D (39.5% and 44.8%), mainly parenteral via. In 2019 they presented higher DDD/100 beds/day: gentamicin (38.74 in the General Hospital and 20.20 in the Maternal Hospital) and ciprofloxacin (31.51 in the General Hospital and 15.00 in the Oncology Hospital); and in 2020 it was cefazolin (41.42 in General Hospital), ciprofloxacin (17.73 in Oncology) and gentamicin (26.99 in Maternal). The highest total costs were for ciprofloxacin and ceftriaxone. Conclusions: The increase in consumption evidenced the need to update therapeutic policies and validation of prescriptions for this group of drugs.
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