The effect of therapeutic feed additive on rumen fermentation in cows with ketosis

Autor: S. R. Sachko
Jazyk: English<br />Ukrainian
Rok vydání: 2023
Předmět:
Zdroj: Біологія тварин, Vol 25, Iss 1, Pp 39-45 (2023)
Druh dokumentu: article
ISSN: 1681-0015
2313-2191
DOI: 10.15407/animbiol25.01.039
Popis: It is known that ionophoric antibiotics regulate ruminal fermentation, improve the utilization of feed protein, and prevent the occurrence of ketosis and steatosis in ruminants. Ionophoric antibiotics and β-acids of hops have a similar spectrum of biological activity, that is, they inhibit the vital activity of most gram-positive microorganisms of the rumen. Bacteria, like other living organisms, need vitamin E as an active antioxidant for cell membranes. The toxicity of tocopherol is very low, so adding it to the diet of ruminants in larger quantities can stimulate celluloselytic rumen bacteria and compensate for the negative effect of ionophores on fiber breakdown. Since rumen bacteria break down a significant part of dietary choline, methionine and carnitine, ruminants must receive them in a protected form, so their influence on rumen fermentation is insignificant. Three groups of cows of the Ukrainian dairy black-spotted breed with milk yields of 5 or more thousand kg during the previous lactation were formed: with signs of clinical ketosis — 4 animals; with subclinical ketosis — 5 animals and clinically healthy — 5 animals. For a month, cows with ketosis were given a treatment supplement containing crushed granules of hop cones (20 g), vitamin E (3 g), and rumen protected choline (50 g), methionine (20 g) and carnitine (1 g). Clinically healthy cows were used as control. In the blood of cows with subclinical ketosis, the additive increased the concentration of glucose and decreased the concentration of β-hydroxybutyrate, these indicators were within the normal range. In cows with symptoms of clinical ketosis, using of the feed additive also reduced the concentration of β-hydroxybutyrate (P
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