Rise of the phoenix: Mucormycosis in COVID-19 times

Autor: Swati A Ravani, Garima A Agrawal, Parth A Leuva, Palak H Modi, Krisha D Amin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Indian Journal of Ophthalmology, Vol 69, Iss 6, Pp 1563-1568 (2021)
Druh dokumentu: article
ISSN: 0301-4738
1998-3689
DOI: 10.4103/ijo.IJO_310_21
Popis: Purpose: Rhino-orbital mucormycosis in times of ongoing COVID-19 pandemic. Aims: The aim of the study was to document cases of rhino-orbital mucormycosis seen at our Regional Institute of Ophthalmology during COVID-19 (coronavirus disease 2019) times. Methods: The study is a retrospective, institutional cohort, interventional study. It was carried out at our Regional Institute of Ophthalmology from September 2020 to mid-March 2021. All patients of biopsy-proven mucormycosis were enrolled in the study. The patients were subjected to complete history taking, ophthalmological examination, and imaging studies. The patients were treated via a multidisciplinary approach with intravenous liposomal amphotericin B and debridement of local necrotic tissue. Exenteration was done when indicated. A minimum 75-day follow-up period was accorded to all study patients. Statistical analysis was done using Chi-square test. A P value ≤0.05 was taken as significant. Results: Thirty-one patients were seen, with a mean age of 56.3 years. The major risk factors included uncontrolled diabetes (96.7%) and COVID-19 positivity (61.2%), with concomitant steroid use in 61.2% patients. The most common presentation was diminution of vision (
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