Autor: |
Christopher O. Barnes, Harry B. Gristick, Natalia T. Freund, Amelia Escolano, Artem Y. Lyubimov, Harald Hartweger, Anthony P. West, Aina E. Cohen, Michel C. Nussenzweig, Pamela J. Bjorkman |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-018-03632-y |
Popis: |
Structure determination of glycosylated HIV-1 envelope (Env) trimers complexed with broadly neutralizing antibodies (bNAbs) promotes a better understanding of bNAb epitopes. Here the authors present the structures of natively-glycosylated Env in complex with the highly-potent bNAb BG18, which is of interest for HIV-1 vaccine development. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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