Ultra-fast, low dose high-pitch (FLASH) versus prospectively-gated coronary computed tomography angiography: Comparison of image quality and patient radiation exposure

Autor: Osama A. Smettei, Sawsan Sayed, Abdullah M Al Habib, Fahad Alharbi, Rami M. Abazid
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of the Saudi Heart Association, Vol 30, Iss 3, Pp 165-171 (2018)
Druh dokumentu: article
ISSN: 1016-7315
DOI: 10.1016/j.jsha.2017.11.001
Popis: Background: Coronary computed tomography angiography (CCTA) is increasingly being used for the evaluation of coronary artery disease; however, radiation exposure remains a major limitation of its use. Objective: To compare image quality and radiation exposure in two groups of patients undergoing CCTA using a 256-slice dual-source helical computed tomography scanner with high-pitch (FLASH) or prospective [step-and-shoot (SAS)] gating protocols. Methods: A prospective, single-center study was performed in our cardiac center. In total, 162 patients underwent CCTA with either FLASH or SAS scanning protocols. Subjective image quality was graded on the basis of a four-point grading system (1, non-diagnostic; 2, adequate; 3, good; 4, excellent). Objective image quality was assessed using image signal, noise, and signal-to-noise ratio (SNR). The effective radiation dose was also estimated. Results: The clinical and demographic characteristics of the patients in both groups were similar. The median age of the patients in both groups was 48.43 years, and males accounted for 63% and 68.7% of the FLASH and SAS groups, respectively. We found that the subjective image quality obtained with the FLASH protocol was superior to that obtained with the SAS protocol (3.35 ± 0.6 mSv vs. 2.82 ± 0.61 mSv; p 0.001) and (21.6 ± 8.7 mSv vs. 16.6 ± 7.7 mSv; p
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