| Autor: |
Anantha Narayanan Ramakrishnan, Josephine Reymann, Christopher Ludtka, Andreas Kiesow, Stefan Schwan |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
BMC Biomedical Engineering, Vol 6, Iss 1, Pp 1-8 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2524-4426 |
| DOI: |
10.1186/s42490-024-00083-z |
| Popis: |
Abstract Background Restorative solutions designed for edentulous patients such as dentures and their accompanying denture adhesives operate in the complex and dynamic environment represented by human oral physiology. Developing material models accounting for the viscoelastic behavior of denture adhesives can facilitate their further optimization within that unique physiological environment. This study aims to statistically quantify the degree of significance of three physiological variables - namely: temperature, adhesive swelling, and pH - on denture adhesive mechanical behavior. Further, based on these statistical significance estimations, a previously-developed viscoelastic material modelling approach for such denture adhesives is further expanded and developed to capture these variables’ effects on mechanical behavior. Methods In this study a comparable version of Denture adhesive Corega Comfort was analysed rheologically using the steady state frequency sweep tests. The experimentally derived rheological storage and loss modulus values for the selected physiological variables were statistically analyzed using multi parameter linear regression analysis and the Pearson’s coefficient technique to understand the significance of each individual parameter on the relaxation spectrum of the denture adhesive. Subsequently, the parameters are incorporated into a viscoelastic material model based on Prony series discretization and time-temperature superposition, and the mathematical relationship for the loss modulus is deduced. Results The results of this study clearly indicated that the variation in both the storage and loss modulus values can be accurately predicted using the oral cavity physiological parameters of temperature, swelling ratio, and pH with an adjusted R 2 value of 0.85. The R 2 value from the multi-parameter regression analysis indicated that the predictor variables can estimate the loss and storage modulus with a reasonable accuracy for at least 85% of the rheologically determined continuous relaxation spectrum with a confidence level of 98%. The Pearson’s coefficient for the independent variables indicated that temperature and swelling have a strong influence on the loss modulus, whereas pH had a weak influence. Based on statistical analysis, these mathematical relationships were further developed in this study. Conclusions This multi-parameter viscoelastic material model is intended to facilitate future detailed numerical investigations performed with implementation of denture adhesives using the finite element method. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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