Association between the triglyceride–glucose index and carotid artery plaque burden in patients with primary hypertension: A cross-sectional study
| Autor: | Shanshan Liu, Hao Zhang, Miao Wu, Zhixian Zhou, Yao Xiao, Qiang Wan, Zhihui Lan, Chao Rong |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Clinical and Experimental Hypertension, Vol 46, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 10641963 1525-6006 1064-1963 |
| DOI: | 10.1080/10641963.2024.2383232 |
| Popis: | Background Studies have shown an association between the triglyceride–glucose (TyG) index and carotid artery plaque (CAP). However, the relationship between the TyG index and plaque burden in individuals with primary hypertension remains uncertain. Our study specifically aimed to explore this relationship among primary hypertension patients.Methods This study involved 5,153 hospitalized patients diagnosed with primary hypertension who were undergoing treatment at the Affiliated Hospital of Jiangxi University of Chinese Medicine. We utilized multivariate logistic regression, penalized spline regression, and generalized additive models to assess the association between the TyG index and CAP burden.Results There were 2,400 patients with primary hypertension in all. The multivariate study, which took into account all covariables, showed a positive correlation between the TyG index and CAP (OR: 1.25, 95% CI: 1.04–1.5). When the TyG index was evaluated as quartiles, the risk of CAP in the Q3 and Q4 levels of the TyG index were 1.4 (95% CI: 1.03–1.91) and 1.54 (95% CI: 1.11–2.14) times greater than in the Q1 level after adjusting for all covariables (P for trend |
| Databáze: | Directory of Open Access Journals |
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