Genome-wide association study for birth, weaning and yearling weight in Colombian Brahman cattle

Autor: Rodrigo Martínez, Diego Bejarano, Yolanda Gómez, Romain Dasoneville, Ariel Jiménez, Gael Even, Johann Sölkner, Gabor Mészáros
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Genetics and Molecular Biology, Vol 40, Iss 2, Pp 453-459 (2017)
Druh dokumentu: article
ISSN: 1678-4685
95225552
DOI: 10.1590/1678-4685-gmb-2016-0017
Popis: Abstract Genotypic and phenotypic data of 1,562 animals were analyzed to find genomic regions that potentially influence the birth weight (BW), weaning weight at seven months of age (WW) and yearling weight (YW) of Colombian Brahman cattle, with genotyping conducted using Illumina Bead chip array with 74,669 SNPs. A Single Step Genomic BLUP (ssGBLP), approach was used to estimate the proportion of variance explained by each marker. Multiple regions scattered across the genome were found to influence weights at different ages, also dependent on the trait component (direct or maternal). The most interesting regions were connected to previously identified QTLs and genes, such as ADAMTSL3, CAPN2, CAPN2, FABP6, ZEB2 influencing growth and weight traits. The identified regions will contribute to the development and refinement of genomic selection programs for Zebu Brahman cattle in Colombia.
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