Engaging Multistakeholder Perspectives to Identify Patient‐Centered Research Priorities Regarding Vaccine Uptake Among Adults With Autoimmune Conditions

Autor: Shilpa Venkatachalam, Kelly Gavigan, Shubhasree Banerjee, Jennifer Gordon, Lisa Emrich, Hope Sullivan, Ashira Blazer, Brittany Banbury, Kimberly N. Weaver, Laura Stradford, Vandana Dronadula, Angela Degrassi, Peter A. Merkel, Dianne G. Shaw, Kalen Larsen, Jeffrey R. Curtis, Robert N. McBurney, Michael D. Kappelman, Michael D. George, W. Benjamin Nowell
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: ACR Open Rheumatology, Vol 5, Iss 6, Pp 290-297 (2023)
Druh dokumentu: article
ISSN: 2578-5745
DOI: 10.1002/acr2.11546
Popis: Objective The study objective was to prioritize topics for future patient‐centered research to increase uptake of common vaccines, such as for pneumococcal pneumonia, influenza, herpes zoster, human papillomavirus, and severe acute respiratory syndrome coronavirus 2, among adults living with autoimmune conditions. Methods A steering committee (SC) was formed that included clinicians, patients, patient advocates, and researchers associated with rheumatic diseases (psoriatic arthritis, rheumatoid arthritis, vasculitis), inflammatory bowel disease, and multiple sclerosis. Through a scoping review and discussions, SC members identified research topics regarding vaccine uptake and/or hesitancy for prioritization. A larger multistakeholder alliance that included patients and patient advocates, clinicians, researchers, policy makers, regulators, and vaccine manufacturers conducted a modified Delphi exercise online with three rating rounds and one ranking round. Frequency analysis and comparisons across stakeholder groups were conducted. A weighted ranking score was generated for each item in the ranking round for final prioritization. Results Through the Delphi process, 33 research topics were identified, of which 13 topics were rated as critical by more than 70% of all stakeholders (n = 31). The two highest ranked critical topics per the full stakeholder group were “How well a vaccine works for adults with autoimmune conditions” and “How beliefs about vaccine safety affect vaccine uptake.” Conclusion A multistakeholder group identified key topics as critically important priorities for future research to decrease vaccine hesitancy and improve uptake of vaccines for adults with autoimmune conditions.
Databáze: Directory of Open Access Journals