| Autor: |
Marios Sotiropoulos, Elise Brisebard, Marine Le Dudal, Gregory Jouvion, Marjorie Juchaux, Delphine Crépin, Catherine Sebrie, Laurene Jourdain, Dalila Labiod, Charlotte Lamirault, Frederic Pouzoulet, Yolanda Prezado |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Clinical and Translational Radiation Oncology, Vol 27, Iss , Pp 44-49 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6308 |
| DOI: |
10.1016/j.ctro.2021.01.001 |
| Popis: |
Minibeam radiation therapy (MBRT) is a type of spatial fractionated radiotherapy that uses submillimetric beams. This work reports on a pilot study on normal tissue response and the increase of the lifespan of glioma-bearing rats when irradiated with a tabletop x-ray system. Our results show a significant widening of the therapeutic window for brain tumours treated with MBRT: an important proportion of long-term survivals (60%) coupled with a significant reduction of toxicity when compared with conventional (broad beam) irradiations. In addition, the clinical translation of the minibeam treatment at a conventional irradiator is evaluated through a possible human head treatment plan. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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