IDENTIFICATION OF POLYMORPHOUS VARIANTS OF GENES REGULATING CELLULAR CYCLE IN CASE OF LUNG CANCER
| Autor: | A. I. Dmitrieva, V. A. Serebryakova, I. A. Kuznetsova, S. S. Rakitin, L. A. Kudyakov, V. V. Novitskiy |
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| Jazyk: | ruština |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Туберкулез и болезни лёгких, Vol 0, Iss 10, Pp 50-53 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2075-1230 2542-1506 |
| Popis: | The study investigated the distribution of polymorphous variants of genes regulating cellular cycle – p53 G215C, Bax G248A and Bcl-2 C938A in lung cancer patients and healthy donors with the purpose of obtaining new fundamental knowledge on the role of above polymorphisms in the lung cancer development. The statistically significant di|erences were found out in the distribution of polymorphous variants of genes regulating cellular cycle in the compared groups; relative risks of cancer development were calculated for those carrying of polymorphous variants of genes of p53 G215C, Bax G248A and Bcl-2 C938A. |
| Databáze: | Directory of Open Access Journals |
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