| Autor: |
Yasui Kozo, Sakata Sonoko, Ochi Hideaki, Itamura Shinji, Hirai Kenta, Takenaka Mieko, Mitani Osamu, Ogawa Kazunori, Iyoda Kuniaki |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Pediatric Rheumatology Online Journal, Vol 10, Iss 1, p 41 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1546-0096 |
| DOI: |
10.1186/1546-0096-10-41 |
| Popis: |
Abstract This report describes 3 year old girl with the unusual presentation of polyarticular juvenile idiopathic arthritis (JIA) with anti-cyclic citrullinated peptide (anti-CCP) antibodies and a positive rheumatoid factor (RF). She was initially treated with a nonsteroidal anti-inflammatory drug (NSAID; ibuprofen) followed by methotrexate (MTX, 10 mg/m2/week) and prednisolone (0.25 mg/kg/day), but these treatments were ineffective. Administration of tocilizumab, a humanized antihuman interleukin-6 receptor monoclonal antibody, promptly improved her clinical manifestations, and she has been in complete remission (DAS28 |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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