The Effects of Varicocelectomy on Sperm DNA Fragmentation and Conventional Semen Parameters in Men with Severe Oligoasthenoteratozoospermia: A Prospective Study

Autor: Chaymae Rochdi, Ibtissam Bellajdel, Anouar EL MOUDANE, Soufiane EL ASSRI, Samira MAMRI, Hafsa TAHERI, Ali Barki, Ahmed Mimouni, Mohammed Choukri
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Fertility and Sterility, Vol 18, Iss 3, Pp 248-255 (2024)
Druh dokumentu: article
ISSN: 2008-076X
2008-0778
DOI: 10.22074/ijfs.2023.2002260.1465
Popis: Background: The dilation and torsion of testicular veins in the plexus pampiniformis causes Varicocele, which is asurgically repairable cause of male infertility. This study assessed the impact of varicocelectomy on semen characteristics,total motile sperm count (TMSC) and sperm DNA integrity in patients with severe oligoasthenoteratozoospermia(OAT).Materials and Methods: In this prospective study, semen samples of 360 men with severe OAT who underwentvaricocelectomy according to World Health Organization (WHO) criteria 2021 were studied (pre-operatively and at 6,12, and 18 months post-operatively).Results: The average age of our patients was 38.5 years. The mean spermatozoa concentration was found to be 1.60 ±0.83 million/ml pre-operatively, while the mean post-operative concentration was 5.17 ± 1.23 million/ml at 6 months,8.32 ± 0.98 million/ml at 12 months, and 13.51 ± 1.48 million/ml at 18 months (P
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