| Autor: |
Jamal Yusuf, Jothinath P, Saibal Mukhopadhyay, Vickram Vignesh, Sanjay Tyagi |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Indian Heart Journal, Vol 70, Iss 2, Pp 206-213 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
0019-4832 |
| DOI: |
10.1016/j.ihj.2017.06.010 |
| Popis: |
Background and aim of the study: Rheumatic mitral stenosis (RMS) is an autoimmune, progressive destructive valve disease occurring as a sequele of streptococcal infection. Epidemiological studies support an association of vitamin D deficiency with initial susceptibility and severity of autoimmune diseases. The aim of the present study was to assess serum level of 25 hydroxyvitamin D in subjects of RMS and assess if any correlation exists with serum levels of vitamin D and severity of disease along with calcification assessed semi-quantitatively by echocardiography by applying Wilkins score. Method: Fifty five patients of RMS without any calcification of the valves (Group A) assessed by echocardiography along with fifty five patients of RMS with mild to moderately calcified valves (Group B, Wilkins calcium score 1 or 2) and 55 patients with severely calcified valves (Group C, Wilkins calcium score 3 or 4) were enrolled for the study. All subjects underwent clinical, echocardiographic, and biochemical evaluation. The total Wilkins score, Wilkins calcium score along with serum level of 25 hydroxyvitamin D was evaluated in all the patients. Results: The median serum level of 25 hydroxyvitamin D was significantly lower in Group B (20.4 ng/ml, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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