MULTICHANNEL INTRALUMINAL IMPEDANCE-PH MEASUREMENT AND ITS OPPORTUNITIES IN CHILDREN WITH GASTROESOPHAGEAL REFLUX DISEASE
| Autor: | S. I. Erdes, A. R. Polishchuk, I. A. Topolskova |
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| Jazyk: | ruština |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Alʹmanah Kliničeskoj Mediciny, Vol 0, Iss 42, Pp 12-22 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2072-0505 2587-9294 |
| DOI: | 10.18786/2072-0505-2015-42-12-22 |
| Popis: | Aim: To review data from clinical studies on a multichannel intraluminal impedance-pH measurement in children with gastroesophageal reflux disease (GERD). Key points: Esophageal pH measurement is considered a golden standard of GERD diagnostics in children. However, this method can identify only the acid reflux. Recently, multichannel intraluminal impedance measurement of esophagus has been introduced into the work-up of such children. This method gives the opportunity to diagnose liquid, gas or mixed types of reflux and to determine whether it is acid, weakly acid or basic, as well as to obtain data on localization of the bolus in the esophagus, its length and direction of movement (antegrade or retrograde). We present the information on normal parameters of multichannel intraluminal impedance and its use for assessment of infants, as well as on changes in its parameters in children with apnoe and on clinical value of non-acid reflux. The significance of multichannel intraluminal impedance in detection of esophageal disorders in patients with otolaryngologic symptoms and other extra-esophageal signs is discussed. Аn association between the results of this method and endoscopic and histological abnormalities found in GERD patients is being actively studied. The authors of the review focus their attention on the data on changes of multichannel intraluminal impedance parameters during treatment of GERD children with proton pump inhibitors. Conclusion: Multichannel intraluminal impedance is a new modern method with wide spectrum of diagnostic opportunities. |
| Databáze: | Directory of Open Access Journals |
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