Research progress of the role of Kisspeptin in puberty onset

Autor: ZHAO Zi-jun, MA Wei
Jazyk: čínština
Rok vydání: 2022
Předmět:
Zdroj: Jichu yixue yu linchuang, Vol 42, Iss 10, Pp 1601-1605 (2022)
Druh dokumentu: article
ISSN: 1001-6325
DOI: 10.16352/j.issn.1001-6325.2022.10.1601
Popis: Kisspeptin activates the hypothalamic-pituitary-gonadal axis (HPGA) and regulates the pulsatile secretion of gonadotropin-releasing hormone (GnRH) through KNDy neurons, thereby regulating the initiation of the pubertal phase. This review focuses on the mechanism of GnRH regulation by Kisspeptin and the role of Kisspeptin in the hypothalamic, pituitary and ovarian, aiming to provide reference for clinical management of abnormal pubertal development.
Databáze: Directory of Open Access Journals