Autor: |
Jing-Hui Li, Si-Zhe Li, Si-Hang Wang, Jie Zhang, Ying-Han Xie, Ya-Gang Zuo |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Frontiers in Medicine, Vol 11 (2024) |
Druh dokumentu: |
article |
ISSN: |
2296-858X |
DOI: |
10.3389/fmed.2024.1417358 |
Popis: |
BackgroundThe coronavirus disease 2019 (COVID-19) pandemic subverted people’s lives and potentially affected the management and prognosis of pre-existing dermatoses. The study aims to identify factors influencing the outcomes of dermatoses during a rapid and widespread Omicron outbreak in China following the adjustment of the COVID-19 policy.Materials and methodsThis retrospective observational study involved outpatients visiting the dermatology department at a tertiary referral hospital in Beijing, China between December 2022 and February 2023. Demographics, COVID-19 characteristics, treatment modalities, and dermatosis outcomes were subjected to statistical analysis.ResultsThe odds ratio (OR) for vitiligo aggravation during COVID-19 was 0.497 [95% confidence interval (CI): 0.254–0.973, p = 0.038] compared to total patients with various dermatoses. Psoriasis patients with a maximum body temperature (Tmax) over 38.6°C during COVID-19 were 2.833 times more likely to experience dermatosis aggravation (OR: 2.833 [1.029–7.803], p = 0.041). Moreover, autoimmune bullous disease (AIBD) patients receiving biologics treatment exhibited a reduced likelihood of aggravation during the COVID-19 outbreak (OR: 0 [0–0.531], p = 0.011).ConclusionVitiligo exhibits lower aggravation rates during COVID-19 than other dermatoses. A higher body temperature during COVID-19 infection can increase the risk of psoriasis aggravation. Biologics treatment reduces the risk of AIBD aggravation during the COVID-19 outbreak. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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