Assessment of Bacterial Profile and Antimicrobial Susceptibility Pattern of Blood Culture Isolates
| Autor: | Kanwal Hassan Cheema, Muhammad Saeed Anwar, Fatima Hameed, Majid Rauf Ahmad, Qanita Fahim, Ayesha Bashir |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of Islamic International Medical College, Vol 17, Iss 1, Pp 9-13 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1815-4018 2410-5422 |
| Popis: | Objective : To determine the pattern of bacterial isolates in bloodstream infections and their antimicrobial susceptibility in a tertiary care hospital, Lahore. Study Design: Descriptive cross-sectional study. Place and Duration of Study: The study was carried out at the Pathology department of Combined Military Hospital, Lahore from November 2019 to January 2020. Materials and Methods: A total of 359 blood culture specimens were collected over a period of three months. Organisms were identified by using API. Antimicrobial susceptibility testing was carried out by Modified Kirby Bauer disk diffusion method on Mueller Hinton agar and interpreted by CLSI guidelines 2019. Results: Out of 359 bacterial isolates, only 11(3.1%) were Gram-positive cocci, whereas 348 (96.9%) isolates were Gram-negative rods (GNRs). Amongst the GNRs, most commonly isolated organism was Salmonella typhi (207; 59.5%) followed by Salmonella paratyphi (60; 17.2%). Twenty-seven (7.7%) Acinetobacter sp., 20 (5.7%) E. coli and 20 (5.7%) Klebsiella sp. were isolated. The antimicrobial resistance pattern of S. typhi showed 158 (76%) MDR and 106 (51%) XDR isolates. Conclusion: The emergence of MDR and XDR bacteria especially amongst Salmonella typhi is quite daunting. Our study emphasizes the importance of antibacterial susceptibilities surveillance in determining the sensitivity pattern of microorganisms causing Blood stream infections. |
| Databáze: | Directory of Open Access Journals |
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