| Autor: |
Athip Nilkaeo |
| Jazyk: |
angličtina |
| Rok vydání: |
2003 |
| Předmět: |
|
| Zdroj: |
Songklanakarin Journal of Science and Technology (SJST), Vol 25, Iss 5, Pp 607-614 (2003) |
| Druh dokumentu: |
article |
| ISSN: |
0125-3395 |
| Popis: |
Interleukin-1 (IL-1), a pro-inflammatory cytokine, has been undergoing clinical evaluation for its anti-neoplastic activity in potentiating the immune response. However, direct effects of this cytokine on cell proliferation in some cancer cells are not well understood. In this study, nonradioactive MTT proliferation assays were employed to investigate the role IL-1 in regulation of proliferation in 5 cell lines. Recombinant human IL-1β treatment resulted in inhibition of cell proliferation as well as the induction of cytotoxicity compared to the untreated control groups (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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