A case of Fournier's gangrene following a large-volume hydrocelectomy in a diabetic patient managed with SGLT-2 inhibitor therapy

Autor: Ethan Vargo, Giovanna Leone, Oren Barat, Aaron Yunker, Neel Parekh
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Urology Case Reports, Vol 39, Iss , Pp 101834- (2021)
Druh dokumentu: article
ISSN: 2214-4420
DOI: 10.1016/j.eucr.2021.101834
Popis: Dapagliflozin (Farxiga), is an SGLT-2 inhibitor commonly indicated for the treatment of diabetes mellitus type 2 (DM 2), heart failure, and chronic kidney disease. One rare side effect associated with SGLT-2 inhibitors is bacterial infection of the genitalia. There are several case reports highlighting the incidence of Fournier's gangrene (FG) in patients who take medications within this drug class. We report a case of FG in a diabetic patient on dapagliflozin who presented following scrotal hydrocelectomy for a large-volume hydrocele. The patient was urgently taken to the operating room for scrotal debridement and recovered well in the post-operative period.
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