Risk Factors of Non-Invasive Ventilation Failure in COPD Patients Presenting with Acute Exacerbation
| Autor: | Yusra Arshad, Hudaibiya Ayub, Nimra Akhtar, Quratul Ain Usmani |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Pakistan Journal of Medicine and Dentistry, Vol 13, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2313-7371 2308-2593 |
| DOI: | 10.36283/PJMD13-1/015 |
| Popis: | Background: Non-invasive ventilation (NIV) is the first-line management for acute exacerbation of COPD (AECOPD), but some patients don't improve and need invasive ventilation, leading to high mortality. We conducted a study to determine risk factors associated with NIV outcomes in these patients. Identifying predictive parameters of NIV failure could help timely intervention and prevent mortality. Methods: A Quasi Single Arm study was conducted at a tertiary care Hospital, in Karachi, from July to December 2022. We studied 170 COPD patients admitted to Medicine Department and Medical ICU with acute respiratory failure, among those 170 patients 80 were male and 90 were female, aged above 40 and below 80 years. Results: Among 170 AECOPD patients studied, 38% experienced NIV failure, while 61% had NIV success. In the NIV failure group, 38.46% of patients died in hospital. Most factors like quadrant infiltrate, weak cough reflex, low consciousness level, more requirements of oxygen, low pH, more respiratory rate, and positive blood cultures (p-value |
| Databáze: | Directory of Open Access Journals |
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