Acute colchicine overdose: report of three cases

Autor:	A. Aghabiklooei, N. Zamani, H. Hassanian-Moghaddam, S. Nasouhi, M. Mashayekhian
Jazyk:	English<br />Italian
Rok vydání:	2014
Předmět:	Colchicine Acute toxicity Fulminant aplasia Disseminated intravascular coagulopathy Outcome Treatment Acute respiratory distress syndrome. Medicine Internal medicine RC31-1245
Zdroj:	Reumatismo, Vol 65, Iss 6, Pp 307-311 (2014)
Druh dokumentu:	article
ISSN:	0048-7449 2240-2683
DOI:	10.4081/reumatismo.2013.720
Popis:	Intentional acute toxicity by colchicine is not common but accompanies a high rate of complications and mortality. It is generally assumed to be an emergency in clinical toxicology. Rapid diagnosis and treatment can prevent death. The most common causes of death in this toxicity are acute cardiac failure, shock, and dysrhythmias with hematopoietic complications occurring in later stages. We report three cases of acute colchicine toxicity, two of which expired, with different presenting and ongoing signs and symptoms. We aimed to define the different possible clinical manifestations of the toxicity and review the probable treatments available for these patients.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/6f5264b8046944b4916c246f8d1dbe23 Zobrazit plný text záznamu View record in DOAJ