Autor: |
Min Hyuk Choi, Dokyun Kim, Jihyun Kim, Young Goo Song, Seok Hoon Jeong |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Journal of Microbiology, Immunology and Infection, Vol 57, Iss 1, Pp 97-106 (2024) |
Druh dokumentu: |
article |
ISSN: |
1684-1182 |
DOI: |
10.1016/j.jmii.2023.11.008 |
Popis: |
Background: This study was designed to determine changes in risk factors on the prognosis of patients during each period of the bloodstream infection (BSI) timeline. Methods: Through an integrated study of multivariable regressions with machine learning techniques, the risk factors for mortality during each period of BSI were analyzed. Results: A total of 302,303 inpatients who underwent blood cultures during 2011–2021 were enrolled. More than 8 % of BSI cases progressed to subsequent BSI, and risk factors were identified as gut colonization with vancomycin-resistant enterococci (aOR 1.82; 95 % CI 1.47–2.24), intensive care unit admission (aOR 3.37; 95 % CI 3.35–4.28), and current cancer chemotherapy (aOR 1.54; 95 % CI 1.36–1.74). The mean SOFA score of the deceased patients during the first 7 days was 10.6 (SD 4.3), which was significantly higher than those on days 8–30 (7.0 ± 4.2) and after Day 30 (4.0 ± 3.5). BSIs caused by Acinetobacter baumannii and Candida albicans were more likely to result in deaths of patients for all time periods (all, P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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