| Autor: |
Lukas Müller, Felix Hahn, Timo Alexander Auer, Uli Fehrenbach, Bernhard Gebauer, Johannes Haubold, Sebastian Zensen, Moon-Sung Kim, Michel Eisenblätter, Thierno D. Diallo, Dominik Bettinger, Verena Steinle, De-Hua Chang, David Zopfs, Daniel Pinto dos Santos, Roman Kloeckner |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Frontiers in Oncology, Vol 12 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2234-943X |
| DOI: |
10.3389/fonc.2022.850454 |
| Popis: |
ObjectivesRecently, several scoring systems for prognosis prediction based on tumor burden have been promoted for patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE). This multicenter study aimed to perform the first head-to-head comparison of three scoring systems.MethodsWe retrospectively enrolled 849 treatment-naïve patients with HCC undergoing TACE at six tertiary care centers between 2010 and 2020. The tumor burden score (TBS), the Six-and-Twelve score (SAT), and the Seven-Eleven criteria (SEC) were calculated based on the maximum lesion size and the number of tumor nodes. All scores were compared in univariate and multivariate regression analyses, adjusted for established risk factors.ResultsThe median overall survival (OS) times were 33.0, 18.3, and 12.8 months for patients with low, medium, and high TBS, respectively (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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