Synthesis of Some New Benzoxazepine Compounds Form Derivatives of Schiff Bases
| Autor: | Amena A. Ahmed, Ahmad Kh. Ahmad, Natiq G. Ahmed |
|---|---|
| Jazyk: | Arabic<br />English |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | مجلة التربية والعلم, Vol 29, Iss 1, Pp 218-232 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1812-125X 2664-2530 |
| DOI: | 10.33899/edusj.2020.164374 |
| Popis: | This study involved synthesize (1,3) oxazepine. The step 1 includes the preparation of compound (1), (5-Bromo-2-mercapto-6-(4-methoxyphenyl) pyrimidin-4(3H)-one), by the condensation of anisaldehyde and ethylbromoacetat and thiourea in EtOH. In the step2, chalcones (2-6) have been produced. The reaction of compound (1) with chalcones (2-6) that gives azo Michael adduct (7-11) is made in the third step. Schiff’s bases (12-16) were prepared by the reaction ketones (7-11) with 2,4-dinitroaniline. Finally preparation of new benzo [1,3] oxazepine compounds (17-21) are prepared by the reaction of phthalic anhydride with Schiff’s bases. The synthesized compounds are identified by physical (melting points, colour change) and spectral methods such as (IR, proton-nmr). |
| Databáze: | Directory of Open Access Journals |
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