Immune landscape and prognostic index for pancreatic cancer based on TCGA database and in vivo validation

Autor: Pan-ling Xu, Chien-shan Cheng, Ting Wang, Shu Dong, Ping Li
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 1471-2407
DOI: 10.1186/s12885-023-10597-9
Popis: Highlights M0 macrophages accounted for more than 9.8%, indicating a poor prognosis in pancreatic cancer. M0 macrophages proportion were negatively correlated with CD8 + T cells, and immune scores. M0 macrophages promote pancreatic cancer growth in vivo. Elimination of M0 macrophages may be a promising strategy against PAAD.
Databáze: Directory of Open Access Journals
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